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LNP delivery system excipient mPEG-DSPE-2K

140.00 USD ($)/Gram

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Product Details:

Shelf Life 24 Months
Taste Other
Smell No Smell
Storage Freezer
HS Code 3907209090
Molecular Formula C45H87NNaO11P
Solubility Sparingly soluble in Chloroform and Methanol
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LNP delivery system excipient mPEG-DSPE-2K Price And Quantity

Price 140.00 USD ($)/Gram
Minimum Order Quantity 1 Gram

LNP delivery system excipient mPEG-DSPE-2K Product Specifications

Shelf Life 24 Months
Storage Freezer
Chemical Name 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
Smell No Smell
Taste Other
CAS No 147867-65-0
Grade Medicine Grade
Medicine Name 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
Melting Point 53 ~ 54
Purity(%) Not less than 95.0%
Solubility Sparingly soluble in Chloroform and Methanol
Appearance White or off-white solid
Usage DSPE-MPEG2000 is used as one of the LNP Delivery System Excipients for mRNA medicines or drugs.
Physical Form Powder
Type Other
Molecular Formula C45H87NNaO11P
HS Code 3907209090

LNP delivery system excipient mPEG-DSPE-2K Trade Information

FOB Port Shanghai or Beijing
Supply Ability 10000 Gram Per Month
Delivery Time 10 Days
Sample Available Yes
Sample Policy If order is confirmed we will reimburse the sample cost
Packaging Details 1g/bottle, 5g/bottle or according to the requirements from customers.
Main Export Market(s) Asia Australia North America Western Europe Middle East Africa Eastern Europe South America Central America
Main Domestic Market All India
Certifications ISO

Product Description

MPEG2000-DSPE combines the amphiphilic properties of phospholipids and the hydrophilic polymer properties of PEG. In recent years, its application in drug carriers such as long-circulating liposomes, polymer micelles, and long-circulating nanoparticles has achieved rapid development. According to the management of pharmaceutical excipients in my country, the molecular weight of polyethylene glycol in the MPEG2000-DSPE molecule is about 2000, which is suitable for the preparation of long-circulating liposomes, so that liposomes will not be captured by MPS-rich tissues immediately after intravenous injection. As a result, the circulation time in the blood is prolonged, thereby increasing the chance of entering pathological tissues.

The amount of MPEG2000-DSPE in doxorubicin liposome DOXIL accounted for 20% of the total lipid, and compared with ordinary doxorubicin liposome Mycoet, the kinetic difference was obvious. The plasma half-life of liposomal doxorubicin, DOXIL is 2.5d, while Myocet is only 0.07h.

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DALIAN HANDOM CHEMICALS CO.,LTD.

RM702, Unit 1, Building 21, Liuhe Road, Ganjingzi Dist,Dalian - 116091, Liaoning, China

Phone :--+8615840669648

Mr John Wang (Manager)

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